Second dose of Johnson & Johnson vaccine tremendously boosted immune response, firm stories

Johnson & Johnson, the maker of a single-shot COVID-19 vaccine, reported Wednesday {that a} second dose drastically elevated the antibody response to the delta variant, a discovering that would sway federal authorities to log off on booster photographs.

“With these new information, we additionally see {that a} booster dose of the Johnson & Johnson COVID-19 vaccine additional will increase antibody responses amongst examine contributors who had beforehand acquired our vaccine,” mentioned Mathai Mammen, the worldwide head of Janssen analysis and improvement at Johnson & Johnson.


The corporate reported that the antibody response towards the coronavirus was 9 occasions greater after a second dose than after the primary dose. The preliminary findings from the early stage trials will likely be despatched to federal regulators on the Meals and Drug Administration as proof for the advantages of authorizing booster doses of the vaccine. Nonetheless, full authorization for the booster is probably going additional down the road given the necessity for extra expansive trials.

The one shot was excluded from the Biden administration’s amended steerage final week that might enable folks to get an additional dose of the Pfizer or Moderna vaccines eight months after they acquired the second of two photographs.

The researchers behind the J&J booster trial additionally reported that immune responses remained robust eight months after receiving the one shot, although it’s unclear whether or not scientific tips for a booster of this vaccine will differ from these set for the Pfizer and Moderna photographs.

“We look ahead to discussing with public well being officers a possible technique for our Johnson & Johnson COVID-19 vaccine, boosting eight months or longer after the first single-dose vaccination,” Mammen mentioned.

The J&J vaccine, which was the latest to be granted emergency use authorization by the FDA, accounts for practically 14 million photographs given in america, federal information exhibits . So far, over 73% of adults have acquired not less than one shot of a vaccine, and practically 63% are absolutely vaccinated.

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